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Pharmacology NSAIDs, Gout and Rheumatoid Ahritis ccdace0a

NSAID proposed to be acting inhibition of COX-3 is:

A
Nimesulide
B
Paracetamol
C
Ketorolac
D
Rofecoxib
High-Yield Explanation
- Paracetamol or acetaminophen has antipyretic and analgesic activities but it lacks anti-inflammatory action. - It is presumed to become inactive by peroxides generated at the site of inflammation therefore, lacks anti- inflammatory action. - Some theories suggest that PCM acts on COX-3 receptors in brain. - A metabolite of paracetamol is assumed to work through vanilloid receptor TRPV-1.

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