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Medicine Haematology ccc5893b

All are true regarding fetal RBC&;s Except -

A
Elevated 2,3 DPG
B
Decreased carbonic anhydrase activity
C
Decreased life span
D
High RBC volume
High-Yield Explanation
<p>The difference in physiochemical propeies when compared with Hb A are: increased solubility of deoxy HbF,slower electrophoretic mobility for HbF,increased resistance of UnFounately to alkali denaturation,HbF has decreased interaction with 2,3-BPG.Thus increase in oxygen affinity is physiologically advantageous in facilitating transplacental oxygen transpo due to diminished binding of 2,3-BPG.</p><p>Reference :DM Vasudevan textbook of biochemistry sixth edition pg no 259</p>

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