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Pharmacology General ccc1cd27

All of the following statements about the use of spironolactone in CHF are true except:

A

It should be administered in low doses to prevent hyperkalemia

B

It affords prognostic benefit in severe heart failure over and above that afforded by ACE inhibitors

C

It helps to overcome the refractoriness to thiazides

D

It affords rapid symptomatic relief in CHF patients

High-Yield Explanation

Loop diuretics are used to provide rapid symptomatic relief whereas aldosterone antagonists decrease the mortality by reversing myocardial remodelling.

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