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Pathology Genetics ccbf3fa5

CGG repeat sequence is found in:

A
Fragile X syndrome
B
Huntingtons chorea
C
Dentatorubropallidolusyian atrophy
D
Machado Joseph disease
High-Yield Explanation
Ans: A (Fragile X syndrome) Ref: Robbins and Co! ran 'Pathologic Basis of Disease' 8th Edition.Elsevier. 2011 Page 168.Explanation:Expansions affecting non-coding regionsDiseaseProteinRepeatingSequenceFragile X syndromeFMR-1 proteinCGGFriednch ataxiaFrataxinGAAMyotonic DystophyMyotonic dystrophy protein kinase (MDPK)CTG(See the following table)

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