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Pediatrics General cc9a4308

Barr body is absent is females having -

A
46 XX genome
B
45 XO genome
C
47 XXX
D
All of the above
High-Yield Explanation
Barr body Discovered by Murray Ban Inactive X-chromosome Usually in female, One X-chromosomes is always inactive and detected as Barr body. Normal 46 XX → One barr body seen Super female 47 XXX → Two barr body seen Klinefelter 47 XXY(males) → Single barr body Turner 45 XD → Barr body absent Barr body is seen in nucleus of neutrophils. Barr body: Sex chromative mass seen within nuclei of normal female somatic cell. Acc. to Lyon hypothesis, one of two x-chromosome in each somatic cell is genetically inactive and repersent barr-body. Klinefilter syndrome (XXY) → One inactive X-chromosome ban body. If XXXY = 2 Ban body XO = 0 Ban body XY = 0 Ban body XX = 1 Ban body

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