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Pharmacology Kidney cc703c42

Free water clearance is decreased by?

A
Vincristine
B
Vinblastine
C
Chlorpropamide
D
Furosemide
High-Yield Explanation
Free water clearance is the volume of blood plasma that is cleared of solute-free water per unit time. Diuretics usually decrease free water clearance by excreting more solutes in the urine free water clearance of zero means the kidney is producing urine isosmotic with respect to the plasma. REF Essentials of Medical Pharmacology, K.D Tripathi,6 th edition, page 564

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