Treatment of choice for cyanide poisoning is

Refer kDT 6/e p527 Administer a cyanide antidote if the diagnosis of cyanide toxicity is strongly suspected, without waiting for laboratory confirmation. Available antidotes are hydroxocobalamin (Cyanokit) and sodium thiosulfate and sodium nitrite (Nithiodote). Both are given intravenously. Patients who present with more than minimal symptoms that resolve without treatment should be admitted for observation and suppoive care. In patients with acute poisoning from hydrogen cyanide (HCN) gas or soluble salts, the principal acute care concerns are hemodynamic instability and cerebral edema. The continuous cardiac monitoring, respiratory and cardiovascular suppo, and frequent neurologic evaluation these patients require is generally best provided in an intensive care unit.