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Pathology General pathology cbca7105

Resolution of inflammation is caused by?

A
TNF Alfa, IL-1 and CRP
B
TNF beta, IL-6 and CRP
C
TNF Alfa, IL 10 and IL 1 receptor antagonist
D
TNF gamma
High-Yield Explanation
Antiinflammatory mediators terminate the acute inflammatory reaction when it is no longer needed the anti-inflammatory cytokines: IL-10, TGF-b, IL-4, IL-13 pro-inflammatory cytokines: IL-1, IL-6, TNF-alpha Interleukin 10 (IL-10) has been proposed as having an inhibitory effect on the production of several inflammatory cytokines including TNF-alpha. ... Lipopolysaccharide-induced TNF-alpha production in peripheral blood monocytes was reduced from 2.035 (0.284) to 0.698 (0.167) ng/ml. ref robbins basic pathology 9th ed page 48

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