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Pharmacology Miscellaneous cbb5a048

Mechanism of action of d-tubocurarine is

A
Competitive, nondepolarizing block at the Nm cholinergic receptor
B
Non - competitive, nondepolarizing block at the Nm cholinergic receptor
C
Competitive, depolarizing block at the Nm cholinergic receptor
D
Noncompetitive, depolarizing block at the Nm cholinergic receptor
High-Yield Explanation
Depolarizing MR - Succinylcholine | - Shoest acting MR - C/I in nerve and muscle injury because it can cause | K+ - Hypehermia can occur. - It causes fasciculations responsible for post-operative muscle pain. Non - Depolarizing or competitive MR d- Tubocurarine - It releases lot of histamine that leads to vasodilation and bronchoconstriction. It competitively inhibit the Nm receptor.

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