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Which of the following statements about oral anticoagulants is FALSE?

A
They interfere with an early step in the synthesis of clotting factors
B
Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days
C
Their dose is adjusted by repeated measurement of prothrombin time
D
They are contraindicated during pregnancy
High-Yield Explanation
(Ref: KDT 6/e p600, 601) Oral anticoagulants inhibit the activation of factor II, VII, IX and X. these do not affect the synthesis of these factors.
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