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Ophthalmology General cada9490

Which of the following antiglaucoma medications can cause drowsiness

A
Latanoprost
B
Timolol
C
Brimonidine
D
Dorzolamide
High-Yield Explanation
Ans. is 'c' i.e., Brimonidine Impoant systemic side effects of topical agents n-blockers : Bronchospasm, bradycardia, .cardiac output, hypotension, depression, impotence, altered lipid profile (hypercholesterolemia). Sympathomimetics Non selective (Dipivefrine, epinephrine) :- Hypeension, arrhythmias Selective a-2 (Brimonidine):- Drowsiness, fatigue, BP changes Selective a-1 & a2 (Apraclonidine) :- Drowsiness, Headache, fatigue Chlinomimetics (Pilocarpine) :- Sweating, salivation, urinary frequency, diarrhea, bronchospasm. Carbonic anhydrase inhibitors (Dorzolamide, brinzolamide) :- Bitter taste, headache, asthenia, renal calculi. Prostaglandin analogues (Latanoprost) :- Headache, symptoms of UI.

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