Pharmacology General ca73ffa5

Tolcapone is

Ototoxic

Nephrotoxic

Hepatotoxic

All of the above

High-Yield Explanation

Tolcapone is a COMT inhibitor used in Parkinson's disease which acts both peripherally & centrally. But it is hepatotoxic. Entacapone is a peripheral COMT inhibitor which is safe in hepatic insufficiency.

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Tolcapone is

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