Pharmacology Chemotherapy ca2755ad

Which of the following drug bind to tubulin and arrest metaphase of the cell cycle?

Vincristine

Carmustine

Infliximab

Methotrexate

High-Yield Explanation

Vinca alkaloids, griseofulvin, taxanes, albendazole act on metaphase of cell cycleVinca alkaloids inhibit polymerization of microtubulesTaxanes inhibit depolymerization of microtubulesGoodman Gillman 12th ed. Pg 1705.

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Which of the following drug bind to tubulin and arrest metaphase of the cell cycle?

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