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Biochemistry Metabolism of nucleic acids c9afd8e3

At physiological pH DNA is

A
Acidic
B
Negatively charged
C
Amphipathic
D
All of the above
High-Yield Explanation
Many proteins interact with DNA at physiological pH because: A. proteins are naturally attracted to DNA regardless of the pH. B. both proteins and DNA are at their isoelectric points at physiological pH and tend to aggregate. C. negatively charged DNA is electrostatically attracted to positively charged regions on proteins. D. proteins and DNA interact using mainly hydrophobic interactions E. positively charged DNA is electrostatically attracted to negatively charged regions on proteins. Ref-Harpers illustrated biochemistry 30/e p549

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