Pharmacology Histamine, 5-HT and PGs c8ed4674

Aspirin is used for secondary prevention of ischemic hea disease because it:-

Inhibits TXA2 synthesis by platelets

Inhibit prostacyclin synthesis

Inhibits release of EDRF

Inhibit synthesis of endothelins

High-Yield Explanation

Aggregatory substances: TXA2 ADP Inhibits aggregation: PGI2. Aspirin is Irreversible inhibitor of COX - thus preventing TXA2 formation & aggregation of PLATELETS.

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Aspirin is used for secondary prevention of ischemic hea disease because it:-

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