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Microbiology Immunology Pa 1 (Immune Response, Antigen-Antibody Reactions, Hypersensitivity, Structure of Immune System, Immunodeficiency Disorders) c8b54767

Myasthenia gravis is which type of hypersensitivity-

A
Type I
B
Type II
C
Type III
D
Type IV
High-Yield Explanation
In mystenia grevis antibodies are directed against Ach Receptors so this a type 2 hypersensitivity reaction. 1. Type II cytotoxic reaction is mediated by antibodies directed against antigens on the cell membrane that activates complement thereby causing antibody-mediated destruction of cells. The cell membrane is damaged by a membrane attack complex during activation of the complement. eg:-Stimulation- Grave's disase (LATS), Inhibition - Myasthenia gravis (Anti Ach receptor Ab) 2.Type 1 rxn lead to anaphylaxis. 3. Type 3 rxn.is antigen antibody complex mediated rxn. Myasthenia gravis, an autoimmune disease

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