Which of the following antimalarial has immunomodulatory effect?
High-Yield Explanation
Hydroxychloroquine is an antimalarial agent with immunosuppressant propeies. It is thought to suppress intracellular antigen processing and loading of peptides onto MHC class II molecules by increasing the pH of lysosomal and endosomal compaments, thereby decreasing T-cell activation. Ref: Katzung 11th edition, Chapter 61.