A 3-year-old boy presented with white reflex in the pupillary area along with mild divergent squint in right eye for 4 months which was noticed by the family members. On examination, leukocoria of right eye with dilated pupil which was non-reactive to light, secondary glaucoma, corneal edema, pseudohypopyon and proptosis were noted. USG B-scan of the eye was done. Eye exam under anesthesia was done. MRI of the region was also done. Which of the following is the most common histopathological finding seen in the above condition: -
High-Yield Explanation
Retinoblastomas are the most common intraocular neoplasm found in childhood and with modern treatment modalities, are, in most cases, curable. On imaging, they are generally characterized by a heterogeneous retinal mass with calcifications, necrotic components and increased vascularization on Doppler ultrasound/enhancement on CT/MRI. IMAGE A IS FLEXNER-WINTERSTEINER ROSETTE (M/C IN RETINOBLASTOMA) IMAGE B IS HOMER-WRIGHT ROSETTE IMAGE C IS PSEUDOROSETTE IMAGE D IS TRUE EPENDYMAL ROSETTE.