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Pathology AIIMS 2019 c685b3d6

Hepcidin inhibits which of the following?

A
Hepheastin
B
DMT-1
C
Cerruloplasmin
D
Ferropoin
High-Yield Explanation
Iron absorption is regulated by hepcidin, a small circulating peptide that is synthesized and released from the liver in response to increases in intrahepatic iron levels. Hepcidin inhibits iron transfer from the enterocyte to plasma by binding to ferropoin and causing it to be endocytosed and degraded.

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