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Pharmacology FMGE 2019 c66d8a95

Antidote for opioid poisoning;

A
Naloxone
B
Pethidine
C
Flumazenil
D
Physostigmine
High-Yield Explanation
Naloxone is an opioid antagonist given intravenously. It blocks mu, kappa and delta receptors. It is the DOC for opioid toxicity. is given parenterally (ineffective orally) and is a very sho acting drug. Pethidine (Meperidine)- fully agonist at opiod receptors Flumazenil-Flumazenil is specific antidote for benzodiazepines. Physostigmine - it is a lipid soluble anticholinesterase. It is the specific antidote for poisoning with belladonna.

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