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Pharmacology General c6513329

Adverse effect of Foscarnet includes all except?

A
Hypercalcemia
B
Hyperkalemia
C
Hypocalcemia
D
Hypokalemia
High-Yield Explanation
Ans. B. HyperkalemiaPotential adverse effects of foscarnet include :-* Renal impairment, hypo- or hypercalcemia, hypo- or hyperphosphatemia, hypokalemia, and hypomagnesemia.* Penile ulceration associated with Foscarnet therapy may be due to high level of ionized drug in the urine.* Nausea, vomiting, anemia, elevation of liver enzymes, and fatigue have been repoed.* The risk of anemia may be additive in patients receiving concurrent zidovudine.* CNS toxicities include headache, hallucinations, and seizures.

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