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Medicine Blood c5f1975b

All of the following are true about para hemophilia except?

A
Due to fracture V deficiency
B
X-link recessive
C
Prolonged PTT and PT
D
All are true
High-Yield Explanation
Ans. B. X-link recessivea. Deficiency of factor V is an autosomal recessive, mild to moderate bleeding disorder that has also been termed parahemophilia. Hemarthroses occur rarely; mucocutaneous bleeding and hematomas are the most common symptoms.b. Severe menorrhagia is a frequent symptom in women. Laboratory evaluation shows prolonged PTT and PT. specific assays for factor V show a reduction in factor V levels.c. FFP is the only currently available therapeutic product that contains factor V. Factor V is lost rapidly from stored FFP.d. Patients with severe factor V deficiency are treated with infusions of FFP at 10mL/kg every 12hr. Rarely, a patient with a negative family history of bleeding has an acquired antibody to factor V. Often, these patients do not bleed because the factor V in platelets prevents excessive bleeding.

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