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Pharmacology Hypeension, Arrhythmias, Dyslipidemia c5b3a14a

Which of the following drugs should be given in sustained release oral dosage form?

A
An anti-arrhythmic drug with a plasma half life of 10 seconds used for acute treatment of PSVT
B
An anti-inflammatory drug with a plasma half life of 24 hr
C
A hypnotic drug with a plasma half life of 2 hours
D
An antihypeensive with a plasma half life of 3 hours
High-Yield Explanation
Sustained release preparation are used for prolonged duration of action of drug . So, used when drug has sho half life and when we require the action of drug for longer duration. Anti-hypeensive drug are used for lifelong. So, sustained release preparations are required. Anti-arrhythmic drugs used in treatment of PSVT are not to be used as sustained release preparation as we need action for only a sho duration. Anti-inflammatory drug with the half life of 24 hrs is already acting for long duration we don't need sustained release preparation. Hypnotic drug with a half life of 2hrs will work for 5-6 hrs. So, no need of sustained release preparation.

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