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Pathology Haematology c5808275

Birbeck granules in the cytoplasm are seen in-

A
Mast cells
B
Langerhan's cells
C
Thrombocytes
D
Myelocytes
High-Yield Explanation
Birbeck granules, also known as Birbeck bodies, are rod shaped or "tennis-racket" cytoplasmic organelles with a central linear density and a striated appearance. First described in 1961 (where they were simply termed "characteristic granules"), they are solely found in Langerhans cells. Although pa of normal Langerhans cell histology, they also provide a mechanism to differentiate Langerhans cell histiocytoses (which are a group of rare conditions collectively known as histiocytoses) from proliferative disorders caused by other cell lines. Formation is induced by langerin.

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