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Medicine C.V.S. c56aa776

Which of the following is/are the characteristics of the vegetations seen in patients with Libmann Sacks' endocarditis?

A
Medium sized
B
Irregular contour
C
Present on the surface of cusps of heart valves
D
All the above
High-Yield Explanation
Ans. is 'd' i.e., All the above* The affection of different valves in different conditions are as follows:VegetationsRheumatic FeverNon Bacterial ThromboticLibman Sacks'Endocarditis (SLE)Infective Endocarditis(Marantic)* Small, warty- Firm- Friable (but less than those of NBTE)* Small* Friable (produce emboli)- Medim sized (small)- Flat, verrucous- Irregular- Large- Bulky- Irregular* Along lines of closure* Along lines of closure* On surface of cusps both surfaces may be involved most common being the undersurface less often on mural endocardium* On upper sur faces of Cusps* Less often on mural Endocardium* Sterile (No organism)* Sterile* Sterile* Non-sterile (bacteria)* No destruction of underlying valves or myocardium* Non destructive* Destructive may damage valve or myocardium* Ulcerates or perforates underlying valve (myocardium)* Seen in Rheumatic fever* Seen in hypercoagulable states eg cancer, promyelocytic leukemia increased estogenic state* Seen in SLE* Seen in infective endocarditis

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