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Pharmacology Adrenergic System c5224bd0

Which of the following is NOT an alpha adrenoceptor agonist?

A
Clonidine
B
Methyldopa
C
Guanabenz
D
Guanfacine
High-Yield Explanation
Ans. (B) Methyldopa(Ref: KDT 8th/e p612)Methyl dopa itself is not an a2 agonist but it is converted to an active metabolite a-methyl norepinephrine which possesses a2 agonistic action. All other drugs listed in the question are a2 agonists for the treatment of hypertension.

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