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Anaesthesia General c520e6fd

Local anaesthetics acts by inhibiting: March 2012

A
Sodium channels
B
Potassium channels
C
Calcium channels
D
Magnesium channels
High-Yield Explanation
Ans: A i.e. Sodium channels Local anaesthetics act by inhibiting sodium channels from inside Local anesthetics Generally blocks: Sodium channels Potency of LA depends on: Lipid solubility Susceptibility of fibres to LA: Type B > type C > type A Amide linked LA: - Lidocaine, - Bupivacaine etc. Ester linked LA: - Cocaine,

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