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Pathology Inflammatory Bowel Disease c4f3a365

A 25-year-old man presents with low grade fever, weight loss, fatigue, crampy abdominal pain, episodic diarrhea & postprandial bloating. Right lower quadrant tenderness is elicited on palpation of abdomen. A capsule endoscopy reveals thickening of terminal ileum, edema, marked luminal narrowing, and a cobblestone appearance of the mucosa. Which of the following is a characteristic of this condition?

A
Additional typical findings include crypt abscesses and pseudopolyps.
B
Inflammation and ulceration limited to mucosa and submucosa with sparing of deeper layers.
C
It can affect any poion of the gastrointestinal tract, but proximal jejunum is most common site of involvement.
D
It can cause fistula formation between loops of affected bowel.
High-Yield Explanation
- Given clinical features suggests the diagnosis of Crohn's disease Discussing options one by one: OPTION 1 : Crypt abscesses & pseudopolyps are seen in ulcerative colitis; not in crohn's disease OPTION 2 : False bacause transmural involvement of intestine is seen in crohn's disease OPTION 3 : Crohn's disease can involve any pa of GIT; but most commonly involved site is ileum OPTION 4 : Stricture & fistula formation is seen in crohn's disease

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