The heavy metal poisoning from mercury affects which pa of the renal tubule?
High-Yield Explanation
Mercury poisoning leads to membranous nephropathy which primarily causes necrosis of proximal convoluted tubular epithelium. Inorganic mercury affects the proximal tubules and cause vesiculation and exfoliation of brush border membrane , followed by calcium influx and cell death. Ref: The Essentials of Forensic Medicine And Toxicology by Dr. K. S. Narayan Reddy 27th edition; Pages 476 - 478; Heptinstall's Pathology Of The Kidney, Volume 1 By J. Charles Jennette page 1122; Robbins textbook of Basic Pathology 7th edition; pages 476 - 478.