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Pathology General c49ce1c6

Which of the following is seen in eosinophil granules?

A
Cathepsin
B
Major basic protein
C
Transferrin
D
All of the above
High-Yield Explanation
Eosinophils are abundant in immune reactions mediated by IgE and in parasitic infections. A chemokine that is especially impoant for eosinophil recruitment is eotaxin. Eosinophils have granules that contain major basic protein, a highly cationic protein that is toxic to parasites but also causes lysis of mammalian epithelial cells. Ref: Robbins 8th edition, Chapter 2.

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