Gynaecomastia is caused by

Ans. is c i.e., Spironolactone Causes of Gynecomastia* Digitalis* Spironolactone* Ethionamide* Ketoconazole* Estrogens* Calcium antagonists* INH* Griseofulvin* Reserpine* Methyldopa* Cimetidine* Phenytoin* Cyproterone acetate* Flutamide* Clomiphene* GoserelinGynecomastia occurs as a result of imbalance between estrogens which stimulate breast tissue and androgens which counteract these effects.The gynecomastia causing drugs can be categorized into :The first type are drugs that act exactly like estrogens, such as diethylstilbestrol, birth control pills, digitalis, and estrogen containing cosmetics.The second type is drugs that enhance endogenous estrogen formation such as gonadotropins and clomiphene.The third type is drugs that inhibit testosterone synthesis and action such as spironolactone, ketoconazole, metronidazole and cimetidine.The final type is drugs that act by unknown mechanisms such as isoniazid, methyldopa, captopril, tricyclic antidepressants, diazepam and heroin.Also know,Testosterone also causes Gynecomastia