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ENT Facial Nerve And Its Disorders c4342263

Which of the following antineoplastic drug causes pulmonary toxicity?

A
Bleomycin
B
5-fluorouracil
C
Cisplatin
D
Vincristine
High-Yield Explanation
Bleomycin causes pulmonary toxicity in the form of pneumonitis, dry cough, rales and later pulmonary fibrosis. These complications occur when total dose of 200 units is exceeded.5-Fluorouracil causes myelosuppression, stomatitis and diarrhoea.Cisplatin is nephrotoxic and ototoxic. Ototoxicity affects 4000 to 8000 Hz which may be permanent.Vincristine is neurotoxic and causes sensory or motor peripheral neuropathy.

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