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Pathology General pathology c3f279d4

The following is not a cell cycle inhibitor

A
P21
B
P27
C
P16/INK4a
D
Cyclin D-CDK4 complex
High-Yield Explanation
Checkpoints Cyclin CDK G1-S Cyclin D CDK 4/6 Cyclin E CDK 2 G2-M Cyclin A CDK 2/1 Cyclin B CDK 1 Family Checkpoints Proteins Functions CIP/KIP (CDKN1) G1-S G2-M p21 p27 p57 p21 induced by p53 p27 responds to TGF-ss INK4/ARF (CDKN2) G1-S p15 p16 p18 p19 p16/INK4a binds to cyclin D/CDK4 & promotes inhibitory effects of RB p14/ARF increased p53 levels by inhibiting MDM2

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