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Biochemistry Enzymes c38bf251

Which of the following liver enzymes is predominantly mitochondrial?

A
SGOT (AST)
B
SGPT (ALT)
C
GGT
D
5' Nucleotidase
High-Yield Explanation
In old literature, it was called as serum glutamate oxaloacetate transaminase (SGOT). AST needs pyridoxal phosphate (vitamin B6) as co-enzyme. Normal serum level of AST ranges from 8 to 20 U/L. It is a marker of liver injury and shows moderate to the drastic increase in parenchymal liver diseases like hepatitis and malignancies of the liver.Ref: DM Vasudevan, Page no: 269

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