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Pathology Nephrotic Syndrome c35dea1a

The pathological feature in Wegener's granulomatosis on renal biopsy is:

A
Nodular glomerulosclerosis
B
Focal necrotizing glomerulonephritis
C
Granulomas in the vascular wall
D
Granuloma of parenchyma of kidney
High-Yield Explanation
Wegener's Granulomatosis : The renal lesions range from a mild/ early disease, where glomeruli show acute focal necrosis with thrombosis of isolated glomerular capillary loops (focal and segmental necrotizing glomerulonephritis). Advanced glomerular lesions are characterized by diffuse necrosis and parietal cell proliferation to form crescents (crescentic glomerulonephritis).

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