Which one of the following is the most significant risk factor for development of gastric carcinoma?
High-Yield Explanation
Risk factors are:Long-term ingestion of high concentration of nitratesH.pyloriIntestinal metaplasia in patients with atrophic gastritisGastric ulcers and adenomatous polypsMenetrier's diseasePatients with blood group A have a higher incidence of Ca stomach than blood group ONote: duodenal ulcers are not associated with gastric cancer.Ref: Harrison's 18/e p766