A 26 year woman presents with a palpable thyroid nodule, and needle biopsy demonstrates amyloid in the stroma of the lesion. A cervical lymph node is palpable on the same side as the lesion, the preferred treatment should be

Ans. is 'c' i.e., Total Thyroidectomy and Modified neck dissection on the side of enlarged lymph node Presence of thyroid nodule along with palpable cervical lymph nodes and amyloid histologically is clearly indicative of Medullary Carcinoma Thyroid. Total Thyroidectomy is the treatment of choice for patients with MTC because of high incidence of multicentricity, the more aggressive course and RAI therapy usually being not effective. In patients with palpable cervical nodes, ipsilateral or bilateral modified radical neck dissection is done.