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Pediatrics Lysosomal Storage Diseases c337660e

A one-year-old boy presented with hepatosplenomegaly and delayed milestones. The liver biopsy and bone marrow biopsy revealed presence of histiocytes with PAS positive cytoplasm. Electron microscopic examination of these histiocytes is most likely to reveal the presence of:

A
Birbeck granules in the cytoplasm
B
Myelin figures in the cytoplasm
C
Parallel rays of tubular structures in lysosomes
D
Electron dense deposit in the mitochondria
High-Yield Explanation
Given scenario suggests Gaucher disease, in which glucocerebroside in lysosomes seen. Birbeck granules in the cytoplasm- seen in histiocytosis X

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