Pathology All India exam c3338a8e

Hirschsprung's disease is

Is inherited in an Autosomal recessive fashion

Is due to unopposed parasympathetic activity in the affected segment of the bowel

Has an equal incidence in girls and boys

Is seen more frequently in children with Down's syndrome than in the general population

High-Yield Explanation

Is seen more frequently in children with Down's syndrome than in the general population. polygenic inheritance, male>female. Increase in sympathetic activity is due to absence of parasympathetic ganglions in the plexi of Auerbach and Meissner.

Hirschsprung's disease is

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