The use of levodopa is avoided in which of the following patients?

Any drug which increase dopamine in brain causes psychosis.Levodopa should be avoided in patient with psychosis Anti parkinsonism drug can cause psychosis Anti Psychotic drug can cause parkinsonism Multiple sclerosis : Interferon b1a and interferon b1b: The immunomodulatory effects of interferon help to diminish the inflammatory responses that lead to demyelination of the axon sheaths. Glatiramer: Glatiramer is a synthetic polypeptide that resembles myelin protein and may act as a decoy to T-cell attack. Natalizumab: Natalizumab is a monoclonal antibody indicated for MS in patients who have failed first-line therapies.