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General Medicine General c2ad0180

A 40 year old male repoed with recurrent episodes of oral ulcers, large areas of denuded skin and flacid vesiculo-bullous eruptions. Which is the most impoant bed-side investigation helpful in establishing the diagnosis -

A
Gram staining of the blister fluid
B
Culture and sensitivity
C
Skin biopsy and immunoflurescence
D
Tzanck smear from the floor of bulla

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