Wolff-chaikoff effect is ?

Ans. is 'c' i.e., Reduced thyroxine synthesis by iodides Iodine and Iodides Iodine is the fastest acting thyroid inhibitor. Most impoant action is inhibition of hormone release (thyroid constipation); but all facets of thyroid synthesis may be affected. Excess iodide inhibits its own transpo in thyroid cells and may alter the redox potential of cells, thus interfering iodination -reduced TIT3 synthesis ( Wolffichaikoff effect).