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Pharmacology Respiratory system c28d0aa4

Recent oral direct thrombin inhibitor which can be used for prevention of stroke is

A
Dabigatrin
B
Ximelagatran
C
Lepirudin
D
Saxagliptin
High-Yield Explanation
Refer Katzung 11/e p 594 Ximelagatran was the first viral direct thrombin inhibitor approved, however it was later withdrawn because of hepatotoxicity. Recently a new direct thrombin inhibitor Dabigatrin had been approved for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation

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