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Pharmacology G.I.T c220d687

DOC for nephrogenic diabetes insipidus:

A
Mannitol
B
Spironolactone
C
Thiazides
D
Demeclocycline
High-Yield Explanation
Ref: Goodman & Gillman's 13th ed. P 466* Nephrogenic DI may be congenital or acquired. Causes can be:# Hypercalcemia, hypokalemia, post obstructive renal failure, Li+, foscarnet, clozapine, demeclocycline, and other drugs can induce nephrogenic DI.* Thiazide diuretics reduce the polyuria of patients with DI and often are used to treat nephrogenic DI.* DOC for central diabetes insipidus: Desmopressin (V2 receptor agonist)* DOC for nephrogenic diabetes insipidus: Thiazide diuretics.* DOC for lithium induced diabetes insipidus: Amiloride

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