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ENT Otosclerosis c1e93173

All of the following statements about sodium fluoride in otosclerosis are true, except:

A
Acts by inhibiting Proteolytic enzymes in cochlea
B
Acts by inhibiting osteoblastic activity
C
Is contraindicated in chronic nephritis
D
Is indicated in patients with a positive Schwaze sign
High-Yield Explanation
In active cases i.e. when Schwaze sign is present, medical management with sodium fluoride (Na F) is done. Na F accelerates the maturation of the focus by increasing osteoblastic and decreasing osteoclastic activity. It also inhibits the proteolytic enzymes that release cytotoxic chemicals to cochlea.

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