Following are the features of chronic arsenic poisoning except ?

Ans. is 'c' i.e., Black pigmentation of skin There is patchy brown (not black) pigmentation of skin. Chronic arsenic poisoning has four stages : First stage (nutritional and gastrointestinal disturbances) : The earliest sign is gradual emaciation. There is loss of appetite, nausea and intermittent vomiting and diarrhea. Second stage (catarrhal changes) : It resembles common cold, i.e. conjunctivitis, running nose and eyes, coughing etc. Third stage (skin rash) : There is classical 'rain drop pigmentation', i.e. patchy brown pigmentation of skin. At initial stages, there is a vesicular eruption which may resemble nettle rash. Hyperkeratosis of palms and soles occur. There are white transverse bands crossing the nails, known as Mee's line, and indicate periods of arrested growth due to interference with normal metabolism. There is alopecia and exfoliative dermatitis. Fouh stage (nervous disturbances) : There is sensory and motor (i.e. mixed) polyneuropathy, with painful paresthesia of hands and feet and muscle tenderness.