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Pharmacology Antibiotics c10d538f

All the following statements are true regarding beta-lactams except

A
Imipenem should be given with cilastatin
B
Meropenem should be given with cilastatin
C
Aztreonam doesn't show cross resistance with cephalexin
D
Methicillin is given by parenteral route
High-Yield Explanation
Among carbapenems, Imipenem should always be given with cilastatin to prevent renal failure and convulsions. No need to give mero and doripenem with cilastatin.Cross-resistance is not seen with aztreonam among beta-lactams.Methicillin is inactivated by gastric acid so administered parenterally.Ref: Katzung 3rd ed; pg 781

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