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Social & Preventive Medicine National Immunization Schedule 2020-21 c0ecd347

On examination, a 34 weeks pregnant lady was found to be HBsAg. What is the management for neonate delivered by Hep B + patient?

A
Hepatitis B vaccine only
B
Immunoglobulin only
C
Hepatitis B vaccine + Immunoglobulin
D
Immunoglobulin followed by vaccine 6 month later
High-Yield Explanation
Hepatitis B vaccine + Immunoglobulin should be given to a neonate born to mother who is HBsAg positive. The simultaneous administration of HBIG and hepatitis B vaccine is more efficacious than HBIG alone. HBIG does not interfere with the antibody response to the hepatitis B vaccine. This combined procedure is ideal both - for prophylaxis of persons accidentally exposed to blood known to contain hepatitis B virus, and - for prevention of the carrier state in the newborn babies of carrier mothers.

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