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Pharmacology JIPMER 2019 c0a8aae7

Mechanism of resistance of tetracyclines is due to?

A
Drug efflux mechanism
B
Development of inactivating enzymes
C
DNA methylation
D
Cell wall alteration
High-Yield Explanation
Mechanism of Resistance Examples Enzymatic breakdown A: Aminoglycosides B: Beta lactams C: Chloramphenicol Decreased permeability Aminoglycosides Efflux pumps Tetracyclines Altered metabolic pathway Sulfonamides Altered target MRSA Vancomycin, Fluoroquinolones
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