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Medicine Cystic fibrosis & Sleep apnea c0938e6c

An infant has a positive newborn screening test for cystic fibrosis. What cut off of sweat chloride confirms cystic fibrosis?

A
Sweat chloride > 30 mEq/L
B
Sweat chloride > 40 mEq/L
C
Sweat chloride > 50 mEq/L
D
Sweat chloride >60 mEq/L
High-Yield Explanation
The diagnosis of CF rests on the combination of clinical criteria and abnormal CFTR function as documented by sweat tests, nasal PD measurements, and CFTR mutation analysis. More than 60 mEq/L of chloride in sweat is diagnostic of CF when 1 or more other criteria are present.

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